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Triad of polar residues implicated in pH specificity of acidic mammalian chitinase

  1. Andrea M. Olland1,*,
  2. James Strand1,
  3. Eleonora Presman1,
  4. Robert Czerwinski1,
  5. Diane Joseph-McCarthy1,
  6. Rustem Krykbaev2,
  7. Gerhard Schlingmann3,
  8. Rajiv Chopra1,
  9. Laura Lin1,
  10. Margaret Fleming2,
  11. Ron Kriz1,
  12. Mark Stahl1,
  13. William Somers1,
  14. Lori Fitz2,
  15. Lidia Mosyak1

Article first published online: 11 JAN 2009

DOI: 10.1002/pro.63

Issue

Protein Science

Protein Science

Volume 18, Issue 3, pages 569–578, March 2009

Additional Information

How to Cite

Olland, A. M., Strand, J., Presman, E., Czerwinski, R., Joseph-McCarthy, D., Krykbaev, R., Schlingmann, G., Chopra, R., Lin, L., Fleming, M., Kriz, R., Stahl, M., Somers, W., Fitz, L. and Mosyak, L. (2009), Triad of polar residues implicated in pH specificity of acidic mammalian chitinase. Protein Science, 18: 569–578. doi: 10.1002/pro.63

Author Information

  1. 1

    Department of Chemical and Screening Sciences, Structural Biology and Computational Chemistry, Wyeth Research, Cambridge, Massachusetts 02140

  2. 2

    Department of Inflammation, Wyeth Research, Cambridge, Massachusetts 02140

  3. 3

    Department of Chemical and Screening Sciences, Natural Products Discovery, Wyeth Research, Pearl River, New York 10965

*200 Cambridge Park Drive, Cambridge, MA 02140

Publication History

  1. Issue published online: 23 FEB 2009
  2. Article first published online: 11 JAN 2009
  3. Accepted manuscript online: 11 JAN 2009 12:00AM EST
  4. Manuscript Revised: 18 DEC 2008
  5. Manuscript Accepted: 18 DEC 2008
  6. Manuscript Received: 3 NOV 2008

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