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Fast structural dynamics in reduced and oxidized cytochrome c
Article first published online: 22 JAN 2009
DOI: 10.1002/pro.72
Copyright © 2009 The Protein Society
Additional Information
How to Cite
Liu, W., Rumbley, J. N., Englander, S. W. and Wand, A. J. (2009), Fast structural dynamics in reduced and oxidized cytochrome c. Protein Science, 18: 670–674. doi: 10.1002/pro.72
Publication History
- Issue published online: 23 FEB 2009
- Article first published online: 22 JAN 2009
- Accepted manuscript online: 22 JAN 2009 12:00AM EST
- Manuscript Accepted: 7 JAN 2009
- Manuscript Revised: 31 DEC 2008
- Manuscript Received: 8 NOV 2008
Funded by
- NIH. Grant Numbers: GM35940, DK39806, GM31847
- Mathers Foundation
References
- 1( 2001) Dynamic activation of protein function: a view emerging from NMR spectroscopy. Nat Struct Biol 8: 926–931.
- 2, ( 2003) Electron tunneling through proteins. Q Rev Biophys 36: 341–372.
- 3, , , ( 1999) Natural engineering principles of electron tunneling in biological oxidation-reduction. Nature 402: 47–52.
- 4( 1980) Quantum-mechanical tunnelling in biological-systems. Q Rev Biophys 13: 387–564.
- 5( 1956) Theory of oxidation-reduction reactions involving electron transfer. 1. J Chem Phys 24: 966–978.
- 6, ( 2001) Dynamics of biochemical and biophysical reactions: insight from computer simulations. Q Rev Biophys 34: 563–679.
- 7, , ( 1987) Electron-tunneling through covalent and noncovalent pathways in proteins. J Chem Phys 86: 4488–4498.
- 8, , ( 1991) Protein electron-transfer rates set by the bridging secondary and tertiary structure. Science 252: 1285–1288.
- 9, ( 1993) Effective coupling in biological electron-transfer—exponential or complex distance dependence. Science 262: 1247–1249.
- 10, ( 1998) A new framework for electron-transfer calculations—beyond the pathways-like models. J Phys Chem B 102: 7497–7505.
- 11, ( 2000) Dynamically controlled protein tunneling paths in photosynthetic reaction centers. Science 290: 114–117.
- 12( 2003) Conformational reorganisation in interfacial protein electron transfer. Biochem Biophys Acta Bioenerg 1604: 67–76.
- 13, , ( 2006) Characterization of the fast dynamics of protein amino acid side chains using NMR relaxation in solution. Chem Rev 106: 1672–1699.
- 14, , ( 2002) Recombinant equine cytochrome c in Escherichia coli: High-level expression, characterization, and folding and assembly mutants. Biochemistry 41: 13894–13901.
- 15, , , ( 2003) Backbone and side-chain heteronuclear resonance assignments and hyperfine NMR shifts in horse cytochrome c. Prot Sci 12: 2104–2108.Direct Link:
- 16, ( 1982) Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules . 1. Theory and range of validity. J Am Chem Soc 104: 4546–4559.
- 17, , , ( 2008) Re-evaluation of the model-free analysis of fast internal motion in proteins using NMR relaxation. J Phys Chem B 112: 12095–12103.
- 18, , , , , , , , , ( 1994) Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation. Biochemistry 33: 5984–6003.
- 19, ( 2006) Conformational dynamics of calmodulin in complex with the calmodulin-dependent kinase kinase alpha calmodulin-binding domain. Biochemistry 45: 8732–8741.
- 20, , , ( 1995) Measurement of H-2 T-1 and T-1p relaxation-times in uniformly C-13-labeled and fractionally H-2-labeled proteins in solution. J Am Chem Soc 117: 11536–11544.
- 21, ( 1989) Model-independent and model-dependent analysis of the global and internal dynamics of cyclosporine A. J Am Chem Soc 111: 4571–4578.
- 22, , ( 1990) Redox-dependent structure change and hyperfine nuclear magnetic resonance shifts in cytochrome-c. Biochemistry 29: 3494–3504.
- 23, ( 2006) Fast time scale dynamics of protein backbones: NMR relaxation methods, applications, and functional consequences. Chem Rev 106: 1624–1671.
- 24, , , , ( 2001) Main chain and side chain dynamics of a heme protein: N-15 and H-2 NMR relaxation studies of R. capsulatus ferrocytochrome c (2). Biochemistry 40: 6559–6569.
- 25, , , , , ( 2001) Main chain and side chain dynamics of oxidized flavodoxin from Cyanobacterium anabaena. Biochemistry 40: 14744–14753.
- 26, ( 1999) Assignment of N-15 chemical shifts and N-15 relaxation measurements for oxidized and reduced iso-1-cytochrome c. Biochemistry 38: 4480–4492.
- 27, , ( 2002) Protein dynamics and cytochrome c: correlations between ligand vibrations and redox activity. J Am Chem Soc 124: 1846–1847.
- 28, , , , ( 2006) Redox-coupled dynamics and folding in cytochrome c. J Am Chem Soc 128: 7909–7915.
- 29, , , , ( 1998) Determinants of protein hydrogen exchange studied in equine cytochrome c. Prot Sci 7: 739–745.Direct Link:
- 30, , , , , , , ( 2001) A further clue to understanding the mobility of mitochondrial yeast cytochrome c—a N-15 T-1 rho investigation of the oxidized and reduced species. Eur J Biochem 268: 4468–4476.Direct Link:
- 31, , , , ( 1998) Contribution of backbone dynamics to entropy changes occurring on oxidation of cytochrome b (5). Can redox linked changes in hydrogen bond networks modulate reduction potentials? J Phys Chem B 102: 8201–8208.
- 32, ( 1981) Conformation change of cytochrome c. 2. Ferricytochrome c refinement at 1.8 Å and comparison with the ferrocytochrome structure. J Mol Biol 153: 95–115.
- 33, ( 1992) Oxidation state-dependent conformational changes in cytochrome c. J Mol Biol 223: 959–976.
- 34, , , , ( 1999) Solution structure of reduced horse heart cytochrome c. J Biol Inorg Chem 4: 21–31.
- 35, , , , ( 1997) The reorganization energy of cytochrome c revisited J Phys Chem B 101: 825–836.
- 36, , , ( 2007) Conformational entropy in molecular recognition by proteins. Nature 448: 325–329.