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Protein Science

Cover image for Protein Science

May 2006

Volume 15, Issue 5

Pages 949–1225

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      Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design (pages 949–960)

      Louis A. Clark, P. Ann Boriack-Sjodin, John Eldredge, Christopher Fitch, Bethany Friedman, Karl J.M. Hanf, Matthew Jarpe, Stefano F. Liparoto, You Li, Alexey Lugovskoy, Stephan Miller, Mia Rushe, Woody Sherman, Kenneth Simon and Herman Van Vlijmen

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.052030506

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      Expression, purification, and characterization of Thermotoga maritima membrane proteins for structure determination (pages 961–975)

      Linda Columbus, Jan Lipfert, Heath Klock, Ian Millett, Sebastian Doniach and Scott A. Lesley

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.051874706

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      Solution structure of the antifreeze-like domain of human sialic acid synthase (pages 1010–1016)

      Toshiyuki Hamada, Yoko Ito, Takamasa Abe, Fumiaki Hayashi, Peter Güntert, Makoto Inoue, Takanori Kigawa, Takaho Terada, Mikako Shirouzu, Mayumi Yoshida, Akiko Tanaka, Sumio Sugano, Shigeyuki Yokoyama and Hiroshi Hirota

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.051700406

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      The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured (pages 1042–1050)

      Marco Nardini, Dmitri Svergun, Peter V. Konarev, Stefania Spanò, Mauro Fasano, Chiara Bracco, Alessandra Pesce, Alessandra Donadini, Claudia Cericola, Francesco Secundo, Alberto Luini, Daniela Corda and Martino Bolognesi

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.062115406

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      Modulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study (pages 1063–1075)

      Rahul S. Rajan, Tiansheng Li, Mohini Aras, Christopher Sloey, Weston Sutherland, Hiromi Arai, Robert Briddell, Olaf Kinstler, Alexis M.K. Lueras, Yu Zhang, Heather Yeghnazar, Michael Treuheit and David N. Brems

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.052004006

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      Modular organization of FDH: Exploring the basis of hydrolase catalysis (pages 1076–1084)

      Steven N. Reuland, Alexander P. Vlasov and Sergey A. Krupenko

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.052062806

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      Sequential reorganization of β-sheet topology by insertion of a single strand (pages 1085–1092)

      Martin Sagermann, Walter A. Baase and Brian W. Matthews

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.052018006

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      Calorimetric and structural studies of the nitric oxide carrier S-nitrosoglutathione bound to human glutathione transferase P1-1 (pages 1093–1105)

      Ramiro Téllez-Sanz, Eleonora Cesareo, Marzia Nuccetelli, Ana M. Aguilera, Carmen Barón, Lorien J. Parker, Julian J. Adams, Craig J. Morton, Mario Lo Bello, Michael W. Parker and Luis García-Fuentes

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.052055206

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      Tunnel plasticity and quaternary structural integrity of a pentameric protein ring (pages 1106–1114)

      Kenneth J. Woycechowsky, Florian P. Seebeck and Donald Hilvert

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.052044606

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      Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen (pages 1115–1126)

      Nicolas André, Nadia Cherouati, Cécile Prual, Tania Steffan, Gabrielle Zeder-Lutz, Thierry Magnin, Franc Pattus, Hartmut Michel, Renaud Wagner and Christoph Reinhart

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.062098206

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      Crystal structure of the conserved protein TTHA0727 from Thermus thermophilus HB8 at 1.9 Å resolution: A CMD family member distinct from carboxymuconolactone decarboxylase (CMD) and AhpD (pages 1187–1192)

      Kaori Ito, Ryoichi Arai, Emiko Fusatomi, Tomomi Kamo-Uchikubo, Shin-ichi Kawaguchi, Ryogo Akasaka, Takaho Terada, Seiki Kuramitsu, Mikako Shirouzu and Shigeyuki Yokoyama

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.062148506

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      Ligand binding by TPR domains (pages 1193–1198)

      Aitziber L. Cortajarena and Lynne Regan

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.062092506

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      Crystal structure of human peptidoglycan recognition protein Iα bound to a muramyl pentapeptide from Gram-positive bacteria (pages 1199–1206)

      Rongjin Guan, Patrick H. Brown, Chittoor P. Swaminathan, Abhijit Roychowdhury, Geert-Jan Boons and Roy A. Mariuzza

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.062077606

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      pK values of the ionizable groups of proteins (pages 1214–1218)

      Richard L. Thurlkill, Gerald R. Grimsley, J. Martin Scholtz and C. Nick Pace

      Article first published online: 1 JAN 2009 | DOI: 10.1110/ps.051840806

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