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Protein Science

Cover image for Protein Science

April 2010

Volume 19, Issue 4

Pages 625–899

  1. Highlights

    1. Top of page
    2. Highlights
    3. Accelerated Communication
    4. Reviews
    5. Articles
    6. For the Records
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      In this issue

      Article first published online: 24 MAR 2010 | DOI: 10.1002/pro.373

  2. Accelerated Communication

    1. Top of page
    2. Highlights
    3. Accelerated Communication
    4. Reviews
    5. Articles
    6. For the Records
    1. You have free access to this content
  3. Reviews

    1. Top of page
    2. Highlights
    3. Accelerated Communication
    4. Reviews
    5. Articles
    6. For the Records
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      Lessons from the lysozyme of phage T4 (pages 631–641)

      Walter A. Baase, Lijun Liu, Dale E. Tronrud and Brian W. Matthews

      Article first published online: 21 JAN 2010 | DOI: 10.1002/pro.344

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  4. Articles

    1. Top of page
    2. Highlights
    3. Accelerated Communication
    4. Reviews
    5. Articles
    6. For the Records
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      The adapter protein Nck: Role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes (pages 658–669)

      Marcus Lettau, Jennifer Pieper, Alyn Gerneth, Beate Lengl-Janßen, Matthias Voss, Andreas Linkermann, Hendrik Schmidt, Christoph Gelhaus, Matthias Leippe, Dieter Kabelitz and Ottmar Janssen

      Article first published online: 15 JAN 2010 | DOI: 10.1002/pro.334

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      Critical biophysical properties in the Pseudomonas aeruginosa efflux gene regulator MexR are targeted by mutations conferring multidrug resistance (pages 680–692)

      Cecilia Andrésen, Shah Jalal, Daniel Aili, Yi Wang, Sohidul Islam, Anngelica Jarl, Bo Liedberg, Bengt Wretlind, Lars-Göran Mårtensson and Maria Sunnerhagen

      Article first published online: 21 JAN 2010 | DOI: 10.1002/pro.343

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      Structural basis for unfolding pathway-dependent stability of proteins: Vectorial unfolding versus global unfolding (pages 693–702)

      Keisuke Yagawa, Koji Yamano, Takaomi Oguro, Masahiro Maeda, Takehiro Sato, Takaki Momose, Shin Kawano and Toshiya Endo

      Article first published online: 21 JAN 2010 | DOI: 10.1002/pro.346

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      Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry (pages 703–715)

      Hui-Min Zhang, Xiu Yu, Michael J. Greig, Ketan S. Gajiwala, Joe C. Wu, Wade Diehl, Elizabeth A. Lunney, Mark R. Emmett and Alan G. Marshall

      Article first published online: 21 JAN 2010 | DOI: 10.1002/pro.347

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      Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms (pages 731–741)

      Jonathan M. Elkins, Carina Gileadi, Leela Shrestha, Claire Phillips, Jing Wang, João R.C. Muniz and Declan A. Doyle

      Article first published online: 29 JAN 2010 | DOI: 10.1002/pro.349

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      Mining protein dynamics from sets of crystal structures using “consensus structures” (pages 742–752)

      Gerard J. P. van Westen, Jörg K. Wegner, Andreas Bender, Adriaan P. IJzerman and Herman W. T. van Vlijmen

      Article first published online: 29 JAN 2010 | DOI: 10.1002/pro.350

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      Mutations within a human IgG2 antibody form distinct and homogeneous disulfide isomers but do not affect Fc gamma receptor or C1q binding (pages 753–762)

      Sandra Lightle, Serdar Aykent, Nathan Lacher, Vesselin Mitaksov, Kristine Wells, James Zobel and Theodore Oliphant

      Article first published online: 29 JAN 2010 | DOI: 10.1002/pro.352

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      Discovery and characterization of a mammalian amyloid disaggregation activity (pages 836–846)

      Amber N. Murray, James P. Solomon, Ya-Juan Wang, William E. Balch and Jeffery W. Kelly

      Article first published online: 16 FEB 2010 | DOI: 10.1002/pro.363

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      Structural insights into the molecular mechanism of H-NOX activation (pages 881–887)

      Charles Olea Jr., Mark A. Herzik Jr., John Kuriyan and Michael A. Marletta

      Article first published online: 16 FEB 2010 | DOI: 10.1002/pro.357

  5. For the Records

    1. Top of page
    2. Highlights
    3. Accelerated Communication
    4. Reviews
    5. Articles
    6. For the Records
    1. You have free access to this content
      Identifying kinetically stable proteins with capillary electrophoresis (pages 888–892)

      Songjie Zhang, Ke Xia, Wai Keen Chung, Steven M. Cramer and Wilfredo Colón

      Article first published online: 20 JAN 2010 | DOI: 10.1002/pro.336

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