Protein Science

Cover image for Vol. 26 Issue 2

February 2017

Volume 26, Issue 2

Pages 147–388

  1. Issue information

    1. Top of page
    2. Issue information
    3. In This Issue
    4. Articles
    5. Methods and Applications
    1. Issue information (pages 147–150)

      Version of Record online: 29 JAN 2017 | DOI: 10.1002/pro.2999

  2. In This Issue

    1. Top of page
    2. Issue information
    3. In This Issue
    4. Articles
    5. Methods and Applications
    1. You have free access to this content
      In This Issue (page 151)

      Version of Record online: 29 JAN 2017 | DOI: 10.1002/pro.3111

  3. Articles

    1. Top of page
    2. Issue information
    3. In This Issue
    4. Articles
    5. Methods and Applications
    1. Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension (pages 152–162)

      Douglas Marcotte, Mia Rushe, Robert M. Arduini, Christine Lukacs, Kateri Atkins, Xin Sun, Kevin Little, Michael Cullivan, Murugan Paramasivam, Thomas A. Patterson, Thomas Hesson, Timothy D. McKee, Tricia L. May-Dracka, Zhili Xin, Andrea Bertolotti-Ciarlet, Govinda R. Bhisetti, Joseph P. Lyssikatos and Laura F. Silvian

      Version of Record online: 21 OCT 2016 | DOI: 10.1002/pro.3062

    2. Comparison of force fields for Alzheimer's A β42: A case study for intrinsically disordered proteins (pages 174–185)

      Martín Carballo-Pacheco and Birgit Strodel

      Version of Record online: 26 OCT 2016 | DOI: 10.1002/pro.3064

      Molecular dynamics simulations are commonly used to complement experimental studies in the understanding of intrinsically disordered proteins. The validity of these simulations depends on the accuracy of the force fields used to model the system. Here, we compare the accuracy of multiple force fields in representing A inline image, an intrinsically disordered protein associated with Alzheimer's disease.

    3. Effect of fuel concentration and force on collective transport by a team of dynein motors (pages 186–197)

      Anjneya Takshak, Tanushree Roy, Parag Tandaiya and Ambarish Kunwar

      Version of Record online: 26 OCT 2016 | DOI: 10.1002/pro.3065

    4. Aromatic claw: A new fold with high aromatic content that evades structural prediction (pages 208–217)

      Joseph R. Sachleben, Aashish N. Adhikari, Grzegorz Gawlak, Robert J. Hoey, Gaohua Liu, Andrzej Joachimiak, Gaetano T. Montelione, Tobin R. Sosnick and Shohei Koide

      Version of Record online: 10 NOV 2016 | DOI: 10.1002/pro.3069

      PDB Code(s): 5SYQ; 5SYQ

    5. Effect of circular permutation on the structure and function of type 1 blue copper center in azurin (pages 218–226)

      Yang Yu, Igor D. Petrik, Kelly N. Chacón, Parisa Hosseinzadeh, Honghui Chen, Ninian J. Blackburn and Yi Lu

      Version of Record online: 4 NOV 2016 | DOI: 10.1002/pro.3071

      PDB Code(s): 5SYD

    6. The IDL of E. coli SSB links ssDNA and protein binding by mediating protein–protein interactions (pages 227–241)

      Piero R. Bianco, Sasheen Pottinger, Hui Yin Tan, Trong Nguyenduc, Kervin Rex and Umesh Varshney

      Version of Record online: 26 JAN 2017 | DOI: 10.1002/pro.3072

    7. Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors (pages 242–257)

      Kathleen M. Clark, Jermaine L. Jenkins, Nadia Fedoriw and Mark E. Dumont

      Version of Record online: 11 NOV 2016 | DOI: 10.1002/pro.3074

      PDB Code: 5SYT

    8. You have free access to this content
      Protein charge determination and implications for interactions in cell extracts (pages 258–267)

      Ciara Kyne, Kiara Jordon, Dana I. Filoti, Thomas M. Laue and Peter B. Crowley

      Version of Record online: 1 DEC 2016 | DOI: 10.1002/pro.3077

    9. You have full text access to this OnlineOpen article
      Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment (pages 280–291)

      Kanako Kuwasako, Nobukazu Nameki, Kengo Tsuda, Mari Takahashi, Atsuko Sato, Naoya Tochio, Makoto Inoue, Takaho Terada, Takanori Kigawa, Naohiro Kobayashi, Mikako Shirouzu, Takuhiro Ito, Taiichi Sakamoto, Kaori Wakamatsu, Peter Güntert, Seizo Takahashi, Shigeyuki Yokoyama and Yutaka Muto

      Version of Record online: 27 NOV 2016 | DOI: 10.1002/pro.3080

      PDB Code(s): 5GVQ

    10. Mercury(II) binds to both of chymotrypsin's histidines, causing inhibition followed by irreversible denaturation/aggregation (pages 292–305)

      Amanda Stratton, Matthew Ericksen, Travis V. Harris, Nick Symmonds and Todd P. Silverstein

      Version of Record online: 14 JAN 2017 | DOI: 10.1002/pro.3082

    11. You have full text access to this OnlineOpen article
      Oligomerization domains in the glycan-binding receptors DC-SIGN and DC-SIGNR: Sequence variation and stability differences (pages 306–316)

      Ália dos Santos, Andreas Hadjivasiliou, Felipe Ossa, Novandy K. Lim, Aylin Turgut, Maureen E. Taylor and Kurt Drickamer

      Version of Record online: 22 DEC 2016 | DOI: 10.1002/pro.3083

    12. Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme (pages 317–326)

      Lorien J. Parker, Alessio Bocedi, David B. Ascher, Jade B. Aitken, Hugh H. Harris, Mario Lo Bello, Giorgio Ricci, Craig J. Morton and Michael W. Parker

      Version of Record online: 14 DEC 2016 | DOI: 10.1002/pro.3084

      PDB Code(s): 5DCG; 5DAL; 5DAK; 5DDL

    13. Interaction network of the ribosome assembly machinery from a eukaryotic thermophile (pages 327–342)

      Jochen Baßler, Yasar Luqman Ahmed, Martina Kallas, Markus Kornprobst, Fabiola R. Calviño, Marén Gnädig, Matthias Thoms, Gunter Stier, Sherif Ismail, Satyavati Kharde, Nestor Castillo, Sabine Griesel, Sonja Bastuck, Bettina Bradatsch, Emma Thomson, Dirk Flemming, Irmgard Sinning and Ed Hurt

      Version of Record online: 14 JAN 2017 | DOI: 10.1002/pro.3085

      PDB Code(s): 5M3Q; 5M43

    14. New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8 (pages 343–354)

      Aiswarya Premchandar, Anna Kupniewska, Arkadiusz Bonna, Grazyna Faure, Tomasz Fraczyk, Ariel Roldan, Brice Hoffmann, Mélanie Faria da Cunha, Harald Herrmann, Gergely L. Lukacs, Aleksander Edelman and Michał Dadlez

      Version of Record online: 29 JAN 2017 | DOI: 10.1002/pro.3086

  4. Methods and Applications

    1. Top of page
    2. Issue information
    3. In This Issue
    4. Articles
    5. Methods and Applications
    1. The macro domain as fusion tag for carrier-driven crystallization (pages 365–374)

      Rebekka Wild and Michael Hothorn

      Version of Record online: 2 NOV 2016 | DOI: 10.1002/pro.3073

      PDB Code(s): 5LNC

    2. An automated method to evaluate the enzyme kinetics of β-glucosidases (pages 382–388)

      Pavel Klimeš, Pavel Mazura, Dušan Turek and Břetislav Brzobohatý

      Version of Record online: 24 NOV 2016 | DOI: 10.1002/pro.3078