• 1
    Rohmer M, Knani M, Simonin P, Sutter B, Sahm H. Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. Biochem J 1993; 295: 517524.
  • 2
    Steinbacher S, Kaiser J, Wungsintaweekul J, Hecht S, Eisenreich W, Gerhardt S, Bacher A, Rohdich F. Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids. J Mol Biol 2002; 316: 7988.
  • 3
    Eisenstein E, Gilliland GL, Herzberg O, Moult J, Orban J, Poljak RJ, Banerjei L, Richardson D, Howard AJ. Biological function made crystal clear—annotation of hypothetical proteins via structural genomics. Curr Opin Biotechnol 2000; 11: 2530.
  • 4
    Herz S, Wungsintaweekul J, Schuhr CA, Hecht S, Luttgen H, Sagner S, Fellermeier M, Eisenreich W, Zenk MH, Bacher A, et al. Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate. Proc Natl Acad Sci USA 2000; 97: 24862490.
  • 5
    Otwinowski Z, Minor W. Processing of x-ray diffraction data collected in oscillation mode. Methods Enzymol 1997; 276: 307326.
  • 6
    Sheldrick GM. SHELX applications to macromolecules. In: FortierrS, editor. Direct methods for solving macromolecular structures. The Netherlands: Kluwer Academic Publishers; 1998. p 401411.
  • 7
    Otwinowski Z. Maximum likelihood refinement of heavy atom parameters. In: WolfW, EvansPR, LeslieAGW, editors. A conf proceedings: Isomorphous replacement and anomalous scattering. Warrington, UK. Daresbury Laboratory. p 8086.
  • 8
    Cowtan K. “DM”: an automated procedure for phase improvement by density modification. Joint CCP4 and ESF-EACBM Newsletter on Protein Crystallography 1994; 31: 3438.
  • 9
    Brünger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 1998; 54: 905921.
  • 10
    Chook YM, Ke H, Lipscomb WN. Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog. Proc Natl Acad Sci USA 1993; 90: 86008603.
  • 11
    Volz K. A test case for structure-based functional assignment: the 1.2 A crystal structure of the yjgF gene product from Escherichia coli. Protein Sci 1999; 8: 24282437.
  • 12
    Sinha S, Rappu P, Lange SC, Mantsala P, Zalkin H, Smith JL. Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family. Proc Natl Acad Sci USA 1999; 96: 1307413079.