The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site

Authors

  • Lionel Trésaugues,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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    • Lionel Trésaugues, Pål Stenmark, and Herwig Schüler contributed equally to this work.

  • Pål Stenmark,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
    2. Department of Molecular Biology, The Scripps Research Institute, La Jolla, California
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    • Lionel Trésaugues, Pål Stenmark, and Herwig Schüler contributed equally to this work.

  • Herwig Schüler,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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    • Lionel Trésaugues, Pål Stenmark, and Herwig Schüler contributed equally to this work.

  • Susanne Flodin,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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  • Martin Welin,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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  • Tomas Nyman,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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  • Martin Hammarström,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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  • Martin Moche,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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  • Susanne Gräslund,

    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
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  • Pär Nordlund

    Corresponding author
    1. Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden
    • Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden
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