The targets of CAPRI Rounds 13–19

Authors

  • Joël Janin

    Corresponding author
    1. Yeast Structural Genomics, IBBMC, Université Paris-Sud, Orsay, France
    • IBBMC, UMR 8619 CNRS, Bât. 430 Université Paris-Sud, 91405 Orsay, France
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    • The author states no conflict of interest.


Abstract

Seven rounds of CAPRI predictions with a total of 14 targets were held in the period June 2007–November 2009. In addition to protease/inhibitor complexes and complexes with G-proteins, some of the targets displayed novel features presenting new challenges to the predictors: a complex with RNA, a leucine zipper to be built abinitio, and a human-designed protein. Nine targets were unbound or required model building; the other five had a bound component. Thirteen were assessed, and the results show that the predictor and scorer groups submitted two- or three-star (medium or high quality) models for eight of them, one-star (acceptable) models for three but failed on the unbound RNA complex and another unbound target. Proteins 2010. © 2010 Wiley-Liss, Inc.

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