The authors state no conflict of interest.
CASP Progress Reports
CASP9 results compared to those of previous casp experiments†
Article first published online: 14 OCT 2011
Copyright © 2011 Wiley-Liss, Inc.
Proteins: Structure, Function, and Bioinformatics
Volume 79, Issue Supplement S10, pages 196–207, 2011
How to Cite
Kryshtafovych, A., Fidelis, K. and Moult, J. (2011), CASP9 results compared to those of previous casp experiments. Proteins, 79: 196–207. doi: 10.1002/prot.23182
- Issue published online: 9 NOV 2011
- Article first published online: 14 OCT 2011
- Accepted manuscript online: 14 SEP 2011 03:57PM EST
- Manuscript Accepted: 13 AUG 2011
- Manuscript Revised: 13 JUL 2011
- Manuscript Received: 1 MAY 2011
- NIH. Grant Number: LM07085
- protein structure prediction;
- community wide experiment;
The quality of structure models submitted to CASP9 is analyzed in the context of previous CASPs. Comparison methods are similar to those used in previous articles in this series, with the addition of new methods looking at model quality in regions not covered by a single best structural template, alignment accuracy, and progress for template-free models. Progress in this CASP was again modest and statistically hard to validate. Nevertheless, there are several positive trends. There is an indication of improvement in overall model quality for the midrange of template-based modeling difficulty, methods for identifying the best model from a set generated have improved, and there are strong indications of progress in the quality of template-free models of short proteins. In addition, the new examination of a model quality in regions of model not covered by the best available template reveals better performance than had previously been apparent. © Proteins 2011; © 2011 Wiley-Liss, Inc.