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Perspective
Low pesticide rates may hasten the evolution of resistance by increasing mutation frequencies
Article first published online: 14 DEC 2010
DOI: 10.1002/ps.2071
Copyright © 2010 Society of Chemical Industry
Additional Information
How to Cite
Gressel, J. (2011), Low pesticide rates may hasten the evolution of resistance by increasing mutation frequencies. Pest. Manag. Sci., 67: 253–257. doi: 10.1002/ps.2071
Publication History
- Issue published online: 9 FEB 2011
- Article first published online: 14 DEC 2010
- Manuscript Accepted: 25 OCT 2010
- Manuscript Revised: 24 OCT 2010
- Manuscript Received: 3 SEP 2010
- Abstract
- Article
- References
- Cited By
Keywords:
- mutation frequency;
- mutator genes;
- stress-induced mutations;
- resistance;
- low rates
Abstract
At very low pesticide rates, a certain low proportion of pests may receive a sublethal dose, are highly stressed by the pesticide and yet survive. Stress is a general enhancer of mutation rates. Thus, the survivors are likely to have more than normal mutations, which might include mutations leading to pesticide resistance, both for multifactorial (polygenic, gene amplification, sequential allelic mutations) and for major gene resistance. Management strategies should consider how to eliminate the subpopulation of pests with the high mutation rates, but the best strategy is probably to avoid too low application rates of pesticides from the outset. Copyright © 2010 Society of Chemical Industry