Solid lipid particles in lipid films to control the diffusive release of 2-heptanone
Article first published online: 28 JAN 2013
Published 2012. This article is a U.S. Government work and is in the public domain in the USA
Pest Management Science
Volume 69, Issue 8, pages 975–982, August 2013
How to Cite
Bilbao-Sáinz, C., Chiou, B.-S., Glenn, G. M., Gregorsky, K. S., Williams, T. G., Wood, D. F., Klamczynski, A. P. and Orts, W. J. (2013), Solid lipid particles in lipid films to control the diffusive release of 2-heptanone. Pest. Manag. Sci., 69: 975–982. doi: 10.1002/ps.3462
- Issue published online: 9 JUL 2013
- Article first published online: 28 JAN 2013
- Accepted manuscript online: 16 NOV 2012 11:16AM EST
- Manuscript Accepted: 16 NOV 2012
- Manuscript Revised: 25 SEP 2012
- Manuscript Received: 11 JUN 2012
- controlled release;
- solid lipid particles;
Controlled-release formulations of bioactive agents are of increasing interest for effective pest control. Volatile 2-heptanone is a bioactive agent that has shown potential as a pesticide. The aim of this study was to investigate the kinetics of release of 2-heptanone incorporated into lipid films or composite solid lipid particle (SLP) films.
Effective 2-heptanone diffusivity was estimated to be between 0.1 and 2.5 mm2 day−1 during the first week and between 0.05 and 0.1 mm2 day−1 during the next 5 weeks. The films that showed better retention of 2-heptanone were the paraffin lipid films. Inclusion of SLPs into paraffin films increased the release rate of 2-heptanone, mainly owing to a decrease in the film firmness as the composite SLP film became less crystalline and more brittle. In contrast, SLPs decreased the kinetics of 2-heptanone release in Acetem films owing to an increase in the film firmness.
The results indicated that the use of SLPs as a method for controlled release can improve the delivery of the natural pesticide 2-heptanone if the SLPs have good compatibility with the matrix, leading to an increase in firmness of the films without increasing their porosity. Published 2012. This article is a U.S. Government work and is in the public domain in the USA.