Epoxiconazole is extensively used as fungicide in cereals, grapes and other crops worldwide. Rice is one of the world's most important food crops. Many people who depend on rice for their food live in Asia. A method employing liquid chromatography–tandem mass spectrometry was developed for determination of epoxiconazole in brown rice, straw, rice hull, paddy water and soils. Epoxiconazole residues in rice hull, brown rice, straw and soil were also determined.