Evaluation of the acaricidal toxicities of camphor and its structural analogues against house dust mites by the impregnated fabric disc method

Authors

  • Ju-Hyun Jeon,

    1. Department of Bioenvironmental Chemistry and Institute of Agricultural Science and Technology, College of Agriculture and Life Sciences, Chonbuk National University, Jeonju, Republic of Korea
    Search for more papers by this author
  • Ji-Yeon Yang,

    Corresponding author
    1. Department of Bioenvironmental Chemistry and Institute of Agricultural Science and Technology, College of Agriculture and Life Sciences, Chonbuk National University, Jeonju, Republic of Korea
    • Correspondence to: Hoi-Seon Lee and Ji-Yeon Yang, Department of Bioenvironmental Chemistry, College of Agriculture and Life Sciences, Chonbuk National University, Jeonju 561–756, Republic of Korea. E-mail: hoiseon@jbnu.ac.kr and jiyeo0527@jbnu.ac.kr

    Search for more papers by this author
  • Hoi-Seon Lee

    Corresponding author
    1. Department of Bioenvironmental Chemistry and Institute of Agricultural Science and Technology, College of Agriculture and Life Sciences, Chonbuk National University, Jeonju, Republic of Korea
    • Correspondence to: Hoi-Seon Lee and Ji-Yeon Yang, Department of Bioenvironmental Chemistry, College of Agriculture and Life Sciences, Chonbuk National University, Jeonju 561–756, Republic of Korea. E-mail: hoiseon@jbnu.ac.kr and jiyeo0527@jbnu.ac.kr

    Search for more papers by this author

Abstract

BACKGROUND

The acaricidal activities of (±)-camphor structural analogues against house dust mites were evaluated using the impregnated fabric disc bioassay.

RESULTS

The acaricidal effects of camphor and its structural analogues were evaluated against Dermatophagoides farinae and D. pteronyssinus. Based on the LD50 values against D. farinae, (±)-camphor (0.95 µg cm−2) was 38.75 times more effective than N,N-diethyl-m-toluamide (DEET) (36.81 µg cm−2), followed by (+)-camphor (1.41 µg cm−2), (−)-camphor (2.03 µg cm−2) and (1R)-camphor oxime (3.31 µg cm−2) in the impregnated fabric disc bioassay. However, camphor-10-sulfonic acid and camphoric acid had no observable activity against D. farinae or D. pteronyssinus. The acaricidal activities of camphor and its structural analogues against D. pteronyssinus were similar to those against D. farinae.

CONCLUSION

These results indicate that camphor and its structural analogues are suitable for producing acaricidal agents against house dust mites. © 2014 Society of Chemical Industry

Ancillary