Matrix-assisted peptide synthesis on nanoparticles
Version of Record online: 2 JUN 2014
Copyright © 2014 European Peptide Society and John Wiley & Sons, Ltd.
Journal of Peptide Science
Volume 20, Issue 9, pages 675–679, September 2014
How to Cite
2014), Matrix-assisted peptide synthesis on nanoparticles, J. Pept. Sci., 20, 675–679. doi: 10.1002/psc.2664, , , and (
- Issue online: 11 AUG 2014
- Version of Record online: 2 JUN 2014
- Manuscript Accepted: 13 MAY 2014
- Manuscript Revised: 11 MAY 2014
- Manuscript Received: 18 MAR 2014
- magnetic matrix;
- embedded nanoparticle;
- solid phase peptide synthesis
We report a new method for multistep peptide synthesis on polymeric nanoparticles of differing sizes. Polymeric nanoparticles were functionalized via their temporary embedment into a magnetic inorganic matrix that allows multistep peptide synthesis. The matrix is removed at the end of the process for obtaining nanoparticles functionalized with peptides. The matrix-assisted synthesis on nanoparticles was proved by generating various biologically relevant peptides. Copyright © 2014 European Peptide Society and John Wiley & Sons, Ltd.