Evaluation of new immunological targets in neuromyelitis optica (pages 25–32)
Jean-Baptiste Chanson, Ilaria Paolini, Nicolas Collongues, Maria C. Alcaro, Frédéric Blanc, Francesca Barbetti, Marie Fleury, Elisa Peroni, Paolo Rovero, Gabrielle Rudolf, Francesco Lolli, Élisabeth Trifilieff, Anna-Maria Papini and Jérôme de Seze
Article first published online: 28 NOV 2012 | DOI: 10.1002/psc.2470
We compared the reactivity against 19 structurally defined peptides in the sera of 26 patients suffering from neuromyelitis optica and 21 healthy subjects. We found that this neurological autoimmune disease is accompanied by an increased reactivity against three peptides. These findings may be used to improve the diagnosis or the comprehension of the disease.