Efficient charge transport in organic semiconductors is the key for their application in organic electronics. Therefore the most important design ansatz is directed to improve carrier mobilities by means of available tools such as chemical and/or structural modifications of the organic materials. Thereby theoretical input can provide guidelines towards possible realizations of high-mobility or, more general, highly functional materials. The Feature Article by Ortmann et al. (pp. 511–525) provides a systematic review of several charge transport approaches and their capabilities regarding this goal. Special focus is put on the transport mechanism, the mobility anisotropy, and temperature dependence of charge carrier transport. As the central concept the inclusion of the strong coupling of carriers with the vibrating lattice and, hence, the dressing of carriers to polarons is described.