SEARCH

SEARCH BY CITATION

Keywords:

  • phenylpropanoid glycosides;
  • platelet aggregation;
  • blood pressure;
  • rabbits, rats

Abstract

The effects of phenylpropanoid glycosides (PhGs) isolated from Calceolaria and Orobanche on platelet aggregation and blood pressure have been investigated. The PhGs tested were able to interfere with platelet aggregation, producing pro- or antiaggregant effects. On the other hand, none of the PhGs tested had a significant effect on Mood pressure. The results suggest that the effects of PhGs on rabbit platelets may be related to a differential modulation of cAMP-phosphodiesterase.