Pharmacological study of phenylpropanoid glycosides: Platelet aggregation and blood pressure studies in rabbits and rats
Version of Record online: 18 JAN 2006
Copyright © 1993 John Wiley & Sons, Ltd.
Volume 7, Issue 1, pages 81–83, January/February 1993
How to Cite
Capasso, A., Pieretti, S., Di Giannuario, A. and Nicoletti, M. (1993), Pharmacological study of phenylpropanoid glycosides: Platelet aggregation and blood pressure studies in rabbits and rats. Phytother. Res., 7: 81–83. doi: 10.1002/ptr.2650070119
- Issue online: 18 JAN 2006
- Version of Record online: 18 JAN 2006
- Manuscript Revised: 4 JUN 1992
- phenylpropanoid glycosides;
- platelet aggregation;
- blood pressure;
- rabbits, rats
The effects of phenylpropanoid glycosides (PhGs) isolated from Calceolaria and Orobanche on platelet aggregation and blood pressure have been investigated. The PhGs tested were able to interfere with platelet aggregation, producing pro- or antiaggregant effects. On the other hand, none of the PhGs tested had a significant effect on Mood pressure. The results suggest that the effects of PhGs on rabbit platelets may be related to a differential modulation of cAMP-phosphodiesterase.