Hepatitis B surface antigen (HBsAg) inactivation and angiotensin-converting enzyme (ACE) inhibition in vitro by Combretum glutinosum perr. (Combretaceae) extract
Article first published online: 18 JAN 2006
Copyright © 1993 John Wiley & Sons, Ltd.
Volume 7, Issue 1, pages 101–102, January/February 1993
How to Cite
Pousset, J. L., Rey, J. P., Levesque, J., Coursaget, P. and Galen, F. X. (1993), Hepatitis B surface antigen (HBsAg) inactivation and angiotensin-converting enzyme (ACE) inhibition in vitro by Combretum glutinosum perr. (Combretaceae) extract. Phytother. Res., 7: 101–102. doi: 10.1002/ptr.2650070126
- Issue published online: 18 JAN 2006
- Article first published online: 18 JAN 2006
- Manuscript Revised: 3 MAR 1992
- Combretum glutinosum Perr;
- hepatitis B antigen surface inactivation;
- ACE inhibition
Among the aqueous extracts of ten African medicinal plants traditionally used for the treatment of hepatic disease and which can inhibit hepatitis B virus antigen (HBsAg) in vitro, extracts from the leaf decoction of Combretum glutinosum proved to be the most active (100–500 ng/mL−1). With solvents of increasing polarity, a precipitate was isolated from the methanolic phase of this extract which contains gallic tannins and these compounds may be responsible for the effect on angiotensin-converting enzyme (ACE).