Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds
Article first published online: 12 JAN 2009
Copyright © 2009 John Wiley & Sons, Ltd.
Volume 23, Issue 9, pages 1197–1204, September 2009
How to Cite
Nassiri-Asl, M. and Hosseinzadeh, H. (2009), Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds. Phytother. Res., 23: 1197–1204. doi: 10.1002/ptr.2761
- Issue published online: 21 AUG 2009
- Article first published online: 12 JAN 2009
- Manuscript Accepted: 10 NOV 2008
- Manuscript Revised: 8 NOV 2008
- Manuscript Received: 23 FEB 2008
- Vitis vinifera;
- grape seed;
Vitis vinifera, known as the grapevine, is native to southern Europe and Western Asia. Grape seed and skin contain several active components including flavonoids, polyphenols, anthocyanins, proanthocyanidins, procyanidines, and the stilbene derivative resveratrol. Grape seed extract in particular has been reported to possess a broad spectrum of pharmacological and therapeutic effects such as antioxidative, anti-inflammatory, and antimicrobial activities, as well as having cardioprotective, hepatoprotective, and neuroprotective effects. Thus, the present review attempts to give a short overview on the pharmacological, toxicological, and clinical studies of grape and its active components. Copyright © 2009 John Wiley & Sons, Ltd.