Research Article

Effect of CYSTUS052® and green tea on subjective symptoms in patients with infection of the upper respiratory tract

  1. Ulrich Kalus*,
  2. Holger Kiesewetter,
  3. Hartmut Radtke

Article first published online: 14 MAY 2009

DOI: 10.1002/ptr.2876

Issue

Phytotherapy Research

Phytotherapy Research

Volume 24, Issue 1, pages 96–100, January 2010

Additional Information

How to Cite

Kalus, U., Kiesewetter, H. and Radtke, H. (2010), Effect of CYSTUS052® and green tea on subjective symptoms in patients with infection of the upper respiratory tract. Phytotherapy Research, 24: 96–100. doi: 10.1002/ptr.2876

Author Information

  1. Institute of Transfusion Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany

*Charité-Universitätsmedizin Berlin, Institut für Transfusionsmedizin, Campus Charité Mitte, D-10098 Berlin, Germany

Publication History

  1. Issue published online: 24 DEC 2009
  2. Article first published online: 14 MAY 2009
  3. Manuscript Accepted: 24 MAR 2009
  4. Manuscript Revised: 17 MAR 2009
  5. Manuscript Received: 16 OCT 2008

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Keywords:

  • Cistus incanus;
  • CYSTUS052®;
  • green tea;
  • infection of the upper respiratory tract;
  • score of subjective symptoms

Abstract

Examples of medicinal herbs that have been perpetuated along several generations based simply on a folk tradition are Cistus and green tea. The principal active constituents of the genus Cistus and green tea are polyphenolic compounds. Polyphenols exhibit a wide range of antibacterial, antifungal and antiinflammatory effects.

The present work aimed to investigate the clinical effect of a Cistus extract (CYSTUS052®) in comparison with green tea on 300 patients with infections of the upper respiratory tract. Due to the lack of clinical study data on their efficacy in patients, this is a report of the findings of our study on the clinical efficacy of CYSTUS052® in patients with the upper respiratory tract infections (URTIs). This study observed a total of 300 patients (277 completers) treated with CYSTUS052® given in lozenges compared with treatment with an extract of green tea. The patients scored the subjective severity of target symptoms using a predefined scale.

The score of subjective symptoms decreased over the course of treatment with CYSTUS052®, whereas treatment with green tea resulted in a less significant decrease of symptoms. CYSTUS052® therefore proved to be an effective adjuvant for the treatment of respiratory infections. Copyright © 2009 John Wiley & Sons, Ltd.

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