Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum-graecum Extract and Mineral Formulation
Article first published online: 10 FEB 2011
Copyright © 2011 John Wiley & Sons, Ltd.
Volume 25, Issue 9, pages 1294–1300, September 2011
How to Cite
Steels, E., Rao, A. and Vitetta, L. (2011), Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum-graecum Extract and Mineral Formulation. Phytother. Res., 25: 1294–1300. doi: 10.1002/ptr.3360
- Issue published online: 27 AUG 2011
- Article first published online: 10 FEB 2011
- Manuscript Accepted: 26 OCT 2010
- Manuscript Revised: 19 OCT 2010
- Manuscript Received: 19 SEP 2010
- Trigonella foenum-graecum;
- reproductive health;
The aim of the clinical study was to evaluate the effect of Testofen, a standardized Trigonella foenum-graecum (Fenugreek) extract and mineral formulation, on male libido (sexual drive, urge or desire) in a double blind randomized placebo controlled study. The study recruited 60 healthy males aged between 25 and 52, without erectile dysfunction and randomized to an oral dose (two tablets per day) of the active treatment (600 mg Testofen per day) or placebo for 6 weeks. The primary outcome measure was the DISF-SR (male) self-administered QOL total score and the four domain scores. The secondary outcome was specific quality of life parameters. Testofen had an overall positive effect on physiological aspects of libido. In particular, there was a significant increase in the subdomains of sexual arousal and orgasm. Testofen had a positive effect on QOL in self-reported satisfaction with muscle strength, energy and well-being but did not have an effect on mood or sleep. Serum prolactin and testosterone levels remained within the reference range. It was concluded that Testofen demonstrated a significant positive effect on physiological aspects of libido and may assist to maintain normal healthy testosterone levels. Copyright © 2011 John Wiley & Sons, Ltd.