A Double-blind, Placebo-controlled Investigation of the Effects of Passiflora incarnata (Passionflower) Herbal Tea on Subjective Sleep Quality
Version of Record online: 3 FEB 2011
Copyright © 2011 John Wiley & Sons, Ltd.
Volume 25, Issue 8, pages 1153–1159, August 2011
How to Cite
Ngan, A. and Conduit, R. (2011), A Double-blind, Placebo-controlled Investigation of the Effects of Passiflora incarnata (Passionflower) Herbal Tea on Subjective Sleep Quality. Phytother. Res., 25: 1153–1159. doi: 10.1002/ptr.3400
- Issue online: 28 JUL 2011
- Version of Record online: 3 FEB 2011
- Manuscript Accepted: 1 DEC 2010
- Manuscript Revised: 27 NOV 2010
- Manuscript Received: 7 JUN 2010
- Monash University
- Passiflora incarnata;
- herbal tea
Passiflora incarnata is a traditional herbal sedative, anxiolytic and a popular sleep aid used for the treatment of sleep disturbance. Several controlled experiments have demonstrated enhanced sleep in laboratory animals, but clinical trials in humans are lacking. The aim of the present study was to investigate the efficacy of Passiflora incarnata herbal tea on human sleep, as measured using sleep diaries validated by polysomnography (PSG). This study featured a double-blind, placebo-controlled, repeated-measures design with a counterbalanced order of treatments (passionflower vs placebo tea), separated by a 1 week ‘washout’ period. Forty-one participants (18–35 years) were exposed to each treatment for a week, whereby they consumed a cup of the tea and filled out a sleep diary for 7 days, and completed Spielberger's state-trait anxiety inventory on the seventh morning. Ten participants also underwent overnight PSG on the last night of each treatment period. Of six sleep-diary measures analysed, sleep quality showed a significantly better rating for passionflower compared with placebo (t(40) = 2.70, p < 0.01). These initial findings suggest that the consumption of a low dose of Passiflora incarnata, in the form of tea, yields short-term subjective sleep benefits for healthy adults with mild fluctuations in sleep quality. Copyright © 2011 John Wiley & Sons, Ltd.