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Raphanus sativus L. var niger as a source of Phytochemicals for the Prevention of Cholesterol Gallstones

Authors

  • Ibrahim Guillermo Castro-Torres,

    Corresponding author
    1. Instituto de Química, Universidad Nacional Autónoma de México, México, D.F., México
    • Ibrahim Guillermo Castro-Torres, Prof. Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, C.P. 04510, Delegación Coyoacán, México, D.F., México.

      E-mail: ibrahim1002@hotmail.com

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  • Minarda De la O-Arciniega,

    1. Área Académica de Farmacia, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Pachuca de Soto, Hidalgo, México
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  • Janeth Gallegos-Estudillo,

    1. Laboratorio de Productos Naturales, Instituto de Ciencias Básicas, Universidad Veracruzana, Xalapa de Enríquez, Veracruz, México
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  • Elia Brosla Naranjo-Rodríguez,

    1. Laboratorio de Neurofarmacología, Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, México, D.F., México
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  • Miguel Ángel Domínguez-Ortíz

    1. Laboratorio de Productos Naturales, Instituto de Ciencias Básicas, Universidad Veracruzana, Xalapa de Enríquez, Veracruz, México
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Abstract

Raphanus sativus L. var niger (black radish) is a plant of the cruciferous family with important ethnobotanical uses for the treatment of gallstones in Mexican traditional medicine. It has been established that the juice of black radish decreases cholesterol levels in plasma and dissolves gallstones in mice. Glucosinolates, the main secondary metabolites of black radish, can hydrolyze into its respective isothiocyanates and have already demonstrated antioxidant properties as well as their ability to diminish hepatic cholesterol levels; such therapeutic effects can prevent the formation of cholesterol gallstones. This disease is considered a current problem of public health. In the present review, we analyze and discuss the therapeutic effects of the main glucosinolates of black radish, as well as the effects that this plant has on cholesterol gallstones disease. Copyright © 2013 John Wiley & Sons, Ltd.

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