Homology modeling studies of beta(1,3)-D-glucan synthase of Moniliophthora perniciosa (pages 3356–3363)
Antonio Anderson Freitas Pinheiro, Alex Gutterres Taranto, Angelo Amâncio Duarte, Aristóteles Góes Neto, Braz Tavares da Hora Júnior, Gonçalo Amarante Guimarães Pereira, Manoelito Coelho dos Santos Júnior and Sandra Aparecida de Assis
Article first published online: 8 JUN 2012 | DOI: 10.1002/qua.24212
The homology modelling methodology was used to generate a tridimensional model of the beta(1,3)-Dglucan synthase from M. perniciosa. In this enzyme, the binding site is located at amino acids Asp353 and Asp354, and the residues that contribute to this region are consistent with experimental data from the GTenzyme family (Asp345, Asp324, Tyr311).