A novel fragmentation process in the fast-atom bombardment/tandem mass spectra of peptides cationized with Na+, determining the identity of the C-terminal amino acid

Authors

  • Willem Kulik,

    1. Analytical Chemistry Laboratory, University of Utrecht, Croesestraat 77A, NL-3522 AD Utrecht, The Netherlands
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  • Wigger Heerma,

    1. Analytical Chemistry Laboratory, University of Utrecht, Croesestraat 77A, NL-3522 AD Utrecht, The Netherlands
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  • Johan K. Terlouw

    Corresponding author
    1. McMaster University, Department of Chemistry, 1280 Main Street West, Hamilton, Ont. L8S4M1, Canada
    • McMaster University, Department of Chemistry, 1280 Main Street West, Hamilton, Ont. L8S4M1, Canada
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Abstract

The metastable ion spectra of the [M + Na]+ ions generated by fast-atom bombardment of sodium chloride containing oligopeptide samples are shown to produce an intense sequence ion from which the identity of the C-terminal amino acid can be readily established.

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