High- and low-energy tandem mass spectrometry of oxonium ions formed by fast-atom bombardment ionization of a series of diastereoisomeric 1,2-trans-2-deoxy-2-iodoglycosyl azides

Authors

  • Joseph Banoub,

    Corresponding author
    1. Department of Fisheries and Oceans, Science Branch, PO Box 5667, St John's, Newfoundland A1C 5X1, Canada
    2. Laboratoire de Chimie Organique 2, URA CNRS 463, Université Claude Bernard Lyon 1, ESCIL, 43 Bd du 11 Novembre 1918, 69622 Villeurbanne, France
    • Department of Fisheries and Oceans, Science Branch, PO Box 5667, St John's, Newfoundland A1C 5X1, Canada
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  • Michel Becchi,

    1. SCA-CNRS, BP 22, 69390 Vernaison, France
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  • Dominique Lafont,

    1. Laboratoire de Chimie Organique 2, URA CNRS 463, Université Claude Bernard Lyon 1, ESCIL, 43 Bd du 11 Novembre 1918, 69622 Villeurbanne, France
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  • Daniel Fraisse,

    1. SCA-CNRS, BP 22, 69390 Vernaison, France
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  • Gerard Descotes

    1. Laboratoire de Chimie Organique 2, URA CNRS 463, Université Claude Bernard Lyon 1, ESCIL, 43 Bd du 11 Novembre 1918, 69622 Villeurbanne, France
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Abstract

Positive-ion fast-atom bombardment mass spectrometry has aided the structural characterization of a novel series of diastereomeric 1,2-trans-2-deoxy-2-iodoglycosyl azides. Daughter-ion tandem mass spectrometry (MS/MS) analyses (high-energy mass-analysed ion kinetic energy spectrometry and low-energy MS/MS with collisionally-activated dissociation), of the precursor oxonium ions for this series of diastereoisomers provided distinct and reproducible fingerprint patterns which permit discrimination amongst the individual configurations.

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