Characterization of the chemical composition of a block copolymer by liquid chromatography/mass spectrometry using atmospheric pressure chemical ionization and electrospray ionization
Article first published online: 17 JUL 2007
Copyright © 2007 John Wiley & Sons, Ltd.
Rapid Communications in Mass Spectrometry
Volume 21, Issue 16, pages 2629–2637, 30 August 2007
How to Cite
van Leeuwen, S. M., Tan, B., Grijpma, D. W., Feijen, J. and Karst, U. (2007), Characterization of the chemical composition of a block copolymer by liquid chromatography/mass spectrometry using atmospheric pressure chemical ionization and electrospray ionization. Rapid Commun. Mass Spectrom., 21: 2629–2637. doi: 10.1002/rcm.3114
- Issue published online: 17 JUL 2007
- Article first published online: 17 JUL 2007
- Manuscript Accepted: 26 MAY 2007
- Manuscript Revised: 24 MAY 2007
- Manuscript Received: 2 MAY 2007
Liquid chromatography/mass spectrometry (LC/MS) with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) in the positive and negative ion modes was used for the characterization of a block copolymer consisting of methoxy poly(ethylene oxide) (mPEO), an ε-caprolactone (CL) segment and linoleic acid (LA), used as surfactant in water-based latex paints. Chromatographic separation was obtained based on the number of CL units in the polymer species and the presence of an mPEO and/or LA tail. Different ionization methods were found to be complementary and only their combination allowed the qualitative profiling of the chemical composition. The LC/MS method has proven valuable for following the reaction in time, as well as for comparison of different polymeric surfactants. Copyright © 2007 John Wiley & Sons, Ltd.