Present address: University of Cape Town, Division of Medical Biochemistry, N3.06.4 Wernher and Beit Building North, Anzio Road, Observatory 7925, Republic of South Africa
A novel chemical ionization reagent ion for organic analytes: the aquachloromanganese(II) cation [ClMn(H2O)+]
Article first published online: 28 FEB 2012
Copyright © 2012 John Wiley & Sons, Ltd.
Rapid Communications in Mass Spectrometry
Volume 26, Issue 8, pages 940–942, 30 April 2012
How to Cite
Gqamana, P. P., Duan, P., Fu, M., Gallardo, V. and Kenttämaa, H. I. (2012), A novel chemical ionization reagent ion for organic analytes: the aquachloromanganese(II) cation [ClMn(H2O)+]. Rapid Commun. Mass Spectrom., 26: 940–942. doi: 10.1002/rcm.6187
- Issue published online: 28 FEB 2012
- Article first published online: 28 FEB 2012
- Manuscript Accepted: 4 FEB 2012
- Manuscript Revised: 17 DEC 2011
- Manuscript Received: 19 AUG 2011
The reactivity of ClMn(H2O)+ towards small organic compounds (L) was examined in a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. The organic compounds studied are aliphatic and aromatic alcohols, aliphatic amines, ketones, an epoxide, an ether, a thiol and a phosphine. All the reactions lead to the formation of the ClMn(H2O)(L)+ complex, which dissociates by loss of the H2O molecule. In general, the reactions were found to occur with high efficiencies (>85%), indicating them to be exothermic. Electron transfer was also observed between ClMn(H2O)+ and compounds with low ionization energies (IE), to form the molecular ion (L+•) of the analyte. Based on these observations, the IE of ClMn(H2O)+ is approximated to be 8.1 ± 0.1 eV. Thus, the utility of ClMn(H2O)+ as a chemical ionization reagent in mass spectrometry is expected to be limited to organic compounds with IEs greater than 8 eV. Copyright © 2012 John Wiley & Sons, Ltd.