Preceding publication: J. L. M. A. Schlatmann and E. Havinga, Rec. Trav. Chim. 80, 1101 (1961).
Article first published online: 2 SEP 2010
Copyright © 1964 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Recueil des Travaux Chimiques des Pays-Bas
Volume 83, Issue 7, pages 665–671, 1964
How to Cite
Sanders, G. M. and Havinga, E. (1964), Studies on vitamin D and related compounds XVII: The photo-formation of lumisterol. Recl. Trav. Chim. Pays-Bas, 83: 665–671. doi: 10.1002/recl.19640830703
A more detailed presentation will be given in G. M. Sanders, Thesis, Leiden, to be published 1964.
- Issue published online: 2 SEP 2010
- Article first published online: 2 SEP 2010
- Manuscript Received: 16 DEC 1963
A further investigation has been made of the pathway of the photo-formation of lumisterol, which had remained doubtful after the previous analyses of irradiation mixtures, in which lumisterol was determined indirectly3. Experiments using tachysterol3-7-3H reveal that lumisterol is not formed directly from tachysterol to a significant extent. Thin layer chromatograms of mixtures obtained after various times of irradiation starting with solutions of pre-calciferol3 and tachysterol3 indicate the direct formation of lumisterol3 from precalciferol3. The modified scheme of interrelationships between pro- and pre-vitamin D, lumisterol and tachysterol is essentially the one originally postulated by Velluz, Amiard and Goffinet11. The question whether ergosterol and tachysterol yield other photo-products besides precalciferol remains to be investigated.