The new cell culture smallpox vaccine should be offered to the general population
Article first published online: 19 DEC 2002
Copyright © 2003 John Wiley & Sons, Ltd.
Reviews in Medical Virology
Volume 13, Issue 1, pages 5–15, January/February 2003
How to Cite
Bicknell, W. and James, K. (2003), The new cell culture smallpox vaccine should be offered to the general population. Rev. Med. Virol., 13: 5–15. doi: 10.1002/rmv.382
- Issue published online: 19 DEC 2002
- Article first published online: 19 DEC 2002
- Manuscript Accepted: 21 OCT 2002
A series of major factors must be weighed in deciding whether or not, and to what extent, a particular country should consider pre-exposure vaccination for smallpox. These include the risk of a bioterrorist attack using smallpox, the risk of secondary spread from another country, the risks and benefits of vaccination, the effectivenes s of vaccination pre- and post-exposure, the prevalence of immunocompromised persons, the capacity of the medical care delivery system and the wealth of a nation. We review here the issues and variables relevant for policy making, propose a framework for country-specific decision making and suggest the World Health Organization has a key role to play, particularly with regard to lower-income countries. In doing so, we support the proposition. Copyright © 2003 John Wiley & Sons, Ltd.