Musculoskeletal disorders (MSD) as a result of patient handling tasks occur at high rates for nursing staff and other patient care providers. Patient care providers perform high-risk patient handling tasks including lifting, transferring, ambulating, and repositioning patients. Continuous performance of these tasks places a patient care provider at risk for development of a MSD. MSDs affect a healthcare organization financially and impact the core of a hospital—the health of the workforce. The purpose of this research was to study the impact of a safe patient handling and movement program on healthcare worker injury, costs and job satisfaction.