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Stromal alterations as quantitative optical biomarkers of epithelial tumor progression

Authors

  • Shuangmu Zhuo,

    Corresponding author
    1. Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, China
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  • Jianxin Chen

    Corresponding author
    1. Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, China
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  • Conflicts of interest: None.

Summary

Stroma plays an important role during epithelial tumor progression. Probing stroma alteration may become an intrinsic indicator for evaluating epithelial tumor progression. In this review, we summarize our recent works on stromal alterations as quantitative optical biomarkers of epithelial tumor progression by use of nonlinear optical microscopy. SCANNING 36:279–285, 2014. © 2013 Wiley Periodicals, Inc.

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