A population model of prostate cancer incidence
Article first published online: 5 JAN 2006
Copyright © 2006 John Wiley & Sons, Ltd.
Statistics in Medicine
Volume 25, Issue 16, pages 2846–2866, 30 August 2006
How to Cite
Tsodikov, A., Szabo, A. and Wegelin, J. (2006), A population model of prostate cancer incidence. Statist. Med., 25: 2846–2866. doi: 10.1002/sim.2257
- Issue published online: 13 JUL 2006
- Article first published online: 5 JAN 2006
- Manuscript Accepted: 1 APR 2005
- Manuscript Received: 20 OCT 2004
- National Cancer Institute Cancer Intervention and Surveillance Modelling Network. Grant Number: U01 CA97414
- Department of Defense. Grant Number: DAMD 7-03-1-0034
- mixture models;
- prostate cancer
Introduction of screening for prostate cancer using the prostate-specific antigen (PSA) marker of the disease led to remarkable dynamics of the incidence of the disease observed in the last two decades. A statistical model is used to provide a link between dissemination of PSA and the observed transient population responses. The model is used to estimate lead time, overdiagnosis and other relevant characteristics of prostate cancer screening. Copyright © 2006 John Wiley & Sons, Ltd.