A population model of prostate cancer incidence

Authors

  • A. Tsodikov,

    Corresponding author
    1. Department of Public Health Sciences, Division of Biostatistics, University of California Davis, One Shields Avenue, Davis, CA 95616, U.S.A.
    • Department of Public Health Sciences, Division of Biostatistics, University of California Davis, One Shields Avenue, Davis, CA 95616, U.S.A.
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  • A. Szabo,

    1. Huntsman Cancer Institute at the University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, U.S.A.
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  • J. Wegelin

    1. Department of Public Health Sciences, Division of Biostatistics, University of California Davis, One Shields Avenue, Davis, CA 95616, U.S.A.
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Abstract

Introduction of screening for prostate cancer using the prostate-specific antigen (PSA) marker of the disease led to remarkable dynamics of the incidence of the disease observed in the last two decades. A statistical model is used to provide a link between dissemination of PSA and the observed transient population responses. The model is used to estimate lead time, overdiagnosis and other relevant characteristics of prostate cancer screening. Copyright © 2006 John Wiley & Sons, Ltd.

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