This article is a U.S. Government work and is in the public domain in the U.S.A.
Statistical and practical issues in the design of a national probability sample of births for the Vanguard Study of the National Children's Study†
Article first published online: 1 JUN 2010
This article is a U.S. Government work and is in the public domain in the U.S.A. Published in 2010 by John Wiley & Sons, Ltd.
Statistics in Medicine
Volume 29, Issue 13, pages 1368–1376, 15 June 2010
How to Cite
Montaquila, J. M., Brick, J. M. and Curtin, L. R. (2010), Statistical and practical issues in the design of a national probability sample of births for the Vanguard Study of the National Children's Study. Statist. Med., 29: 1368–1376. doi: 10.1002/sim.3891
- Issue published online: 1 JUN 2010
- Article first published online: 1 JUN 2010
- Manuscript Accepted: 27 JAN 2010
- Manuscript Received: 20 FEB 2009
- National Institute for Child Health and Human Development
- NIH. Grant Numbers: HHSN275200503395C, N01-HD-5-3395
- multistage sample;
- area probability sample;
- primary sampling unit;
The National Children's Study is a national household probability sample designed to identify 100 000 children at birth and follow the sampled children for 21 years. Data from the study will support examining numerous hypotheses concerning genetic and environmental effects on the health and development of children. The goals of the study present substantial challenges. For example, the need for preconception, prenatal, and postnatal data requires identifying women in the early stages of pregnancy, the collection of many types of data, and the retention of the children over time. In this paper, we give an overview of the sample design used in a pilot study called the Vanguard Study, and highlight the approaches used to address these challenges. We will also describe the rationale for the sampling choices made at each stage, the unique organizational structure of the NCS and issues we expect to face during implementation. Published in 2010 by John Wiley & Sons, Ltd.