Estimation of a common risk ratio in stratified case-cohort studies
Article first published online: 12 OCT 2006
Copyright © 1992 John Wiley & Sons, Ltd.
Statistics in Medicine
Volume 11, Issue 12, pages 1599–1605, 1992
How to Cite
Sato, T. (1992), Estimation of a common risk ratio in stratified case-cohort studies. Statist. Med., 11: 1599–1605. doi: 10.1002/sim.4780111207
- Issue published online: 12 OCT 2006
- Article first published online: 12 OCT 2006
- Manuscript Revised: MAR 1992
- Manuscript Received: FEB 1992
The case-cohort study design is a useful modification of the case-control design, which allows direct estimation of the risk ratio without the rare-disease assumption. While several risk ratio estimation procedures have been proposed under large-strata settings, only the Mantel-Haenszel point estimator is available in sparse stratifications. This paper provides simple confidence limits methods, based on the large-sample distribution of the Mantel-Haenszel risk ratio, that apply to both large-strata and sparse-data situations. For the Tarone risk ratio, I give a new large-strata variance estimate.