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A generalized Jonckheere test against ordered alternatives for repeated measures in randomized blocks

Authors


Correspondence to: Ying Zhang, Department of Mathematics and Statistics, Acadia University, Wolfville, NS, Canada.

E-mail: ying.zhang@acadiau.ca

Abstract

Focusing on statistical methods in patient-reported outcomes, we propose and develop a generalized Jonckheere test against ordered alternatives for repeated measures in a randomized block design. We derive its asymptotic null distribution properties and describe methods for estimating the null distribution for testing the hypothesis. We present a numerical example to illustrate the test procedure. Copyright © 2012 John Wiley & Sons, Ltd.

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