Randomization at the level of primary care practice: use of pre-intervention data and random effects models
Article first published online: 30 MAY 2001
Copyright © 2001 John Wiley & Sons, Ltd.
Statistics in Medicine
Volume 20, Issue 12, pages 1727–1738, 30 June 2001
How to Cite
Nixon, R. M., Duffy, S. W., Fender, G. R. K., Day, N. E. and Prevost, T. C. (2001), Randomization at the level of primary care practice: use of pre-intervention data and random effects models. Statist. Med., 20: 1727–1738. doi: 10.1002/sim.792
- Issue published online: 30 MAY 2001
- Article first published online: 30 MAY 2001
- Manuscript Accepted: JUL 2000
- Manuscript Received: FEB 1999
The Anglia menorrhagia education study tests the effectiveness of an education package for the treatment of menorrhagia given to doctors at a primary care level. General practices were randomized to receive or not receive the package. It is hoped that this intervention will reduce the proportion of women suffering from menorrhagia that are referred to hospital. Data are available on the treatment and referral of women in the practices in the education and control groups, both pre- and post-intervention. We define and demonstrate a random effects logistic regression model that includes pre-intervention data for calculating the effectiveness of the intervention. Copyright © 2001 John Wiley & Sons, Ltd.