Statistics in Medicine

© John Wiley & Sons, Ltd.

Cover image for Statistics in Medicine

10 September 2009

Volume 28, Issue 20

Pages 2509–2616

  1. Research Articles

    1. Top of page
    2. Research Articles
    1. Should baseline be a covariate or dependent variable in analyses of change from baseline in clinical trials? (pages 2509–2530)

      Guanghan F. Liu, Kaifeng Lu, Robin Mogg, Madhuja Mallick and Devan V. Mehrotra

      Article first published online: 17 JUL 2009 | DOI: 10.1002/sim.3639

    2. Testing treatment effects in unconfounded studies under model misspecification: Logistic regression, discretization, and their combination (pages 2531–2551)

      M. Z. Cangul, Y. R. Chretien, R. Gutman and D. B. Rubin

      Article first published online: 1 JUL 2009 | DOI: 10.1002/sim.3633

    3. Cluster analysis using multivariate mixed effects models (pages 2552–2565)

      Luis Villarroel, Guillermo Marshall and Anna E. Barón

      Article first published online: 17 JUN 2009 | DOI: 10.1002/sim.3632

    4. An adjustment for patient heterogeneity in the design of two-stage phase II trials (pages 2566–2579)

      Richard Sposto and Paul S. Gaynon

      Article first published online: 11 JUN 2009 | DOI: 10.1002/sim.3624

    5. A unified approach for analyzing exchangeable binary data with applications to developmental toxicity studies (pages 2580–2604)

      Xin Dang, Stephine Lena Keeton and Hanxiang Peng

      Article first published online: 22 JUN 2009 | DOI: 10.1002/sim.3638

    6. Estimating variance parameters from multivariate normal variables subject to limit of detection: MLE, REML, or Bayesian approaches? (pages 2605–2616)

      Lei Nie, Haitao Chu and Shibao Feng

      Article first published online: 13 JUL 2009 | DOI: 10.1002/sim.3644

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