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Statistics in Medicine

© John Wiley & Sons, Ltd.

Cover image for Vol. 31 Issue 19

30 August 2012

Volume 31, Issue 19

Pages 2027–2150

  1. Research Articles

    1. Top of page
    2. Research Articles
    1. Adaptive extensions of a two-stage group sequential procedure for testing primary and secondary endpoints (I): unknown correlation between the endpoints (pages 2027–2040)

      Ajit C. Tamhane, Yi Wu and Cyrus R. Mehta

      Article first published online: 22 JUN 2012 | DOI: 10.1002/sim.5372

    2. Adaptive extensions of a two-stage group sequential procedure for testing primary and secondary endpoints (II): sample size re-estimation (pages 2041–2054)

      Ajit C. Tamhane, Yi Wu and Cyrus R. Mehta

      Article first published online: 26 JUN 2012 | DOI: 10.1002/sim.5377

    3. A Bayesian–frequentist two-stage single-arm phase II clinical trial design (pages 2055–2067)

      Gaohong Dong, Weichung Joe Shih, Dirk Moore, Hui Quan and Stephen Marcella

      Article first published online: 13 MAR 2012 | DOI: 10.1002/sim.5330

    4. Practical guidelines for adaptive seamless phase II/III clinical trials that use Bayesian methods (pages 2068–2085)

      Peter K. Kimani, Ekkehard Glimm, Willi Maurer, Jane L. Hutton and Nigel Stallard

      Article first published online: 22 MAR 2012 | DOI: 10.1002/sim.5326

    5. Efficient use of longitudinal CD4 counts and viral load measures in survival analysis (pages 2086–2097)

      S. E. Holte, T. W. Randolph, J. Ding, J. Tien, R. S. McClelland, J. M. Baeten and J. Overbaugh

      Article first published online: 13 MAR 2012 | DOI: 10.1002/sim.5318

    6. A simulation study of finite-sample properties of marginal structural Cox proportional hazards models (pages 2098–2109)

      Daniel Westreich, Stephen R. Cole, Enrique F. Schisterman and Robert W. Platt

      Article first published online: 11 APR 2012 | DOI: 10.1002/sim.5317

    7. Using factor mixture analysis to model heterogeneity, cognitive structure, and determinants of dementia: an application to the Aging, Demographics, and Memory Study (pages 2110–2122)

      C. Viroli

      Article first published online: 13 MAR 2012 | DOI: 10.1002/sim.5320

    8. A spatio-temporal absorbing state model for disease and syndromic surveillance (pages 2123–2136)

      Matthew J. Heaton, David L. Banks, Jian Zou, Alan F. Karr, Gauri Datta, James Lynch and Francisco Vera

      Article first published online: 2 MAR 2012 | DOI: 10.1002/sim.5350

    9. A restricted mixture model for dietary pattern analysis in small samples (pages 2137–2150)

      A. Rita Gaio, Joaquim Pinto da Costa, Ana Cristina Santos, Elisabete Ramos and Carla Lopes

      Article first published online: 13 MAR 2012 | DOI: 10.1002/sim.5336

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