Statistics in Medicine

Cover image for Vol. 32 Issue 10

Special Issue: Papers from the Joint EMA, ISBS and DR-IBS International Symposium on Biopharmaceutical Statistics: Bridging Drug Development from Research to Marketing

10 May 2013

Volume 32, Issue 10

Pages 1619–1791

Issue edited by: Franz Koenig, Frank Bretz

  1. Preface

    1. Top of page
    2. Preface
    3. Special Issue Papers
  2. Special Issue Papers

    1. Top of page
    2. Preface
    3. Special Issue Papers
    1. On the efficiency of two-stage response-adaptive designs (pages 1646–1660)

      Holger Dette, Björn Bornkamp and Frank Bretz

      Version of Record online: 2 AUG 2012 | DOI: 10.1002/sim.5555

    2. On the choice of doses for phase III clinical trials (pages 1661–1676)

      Vera Lisovskaja and Carl-Fredrik Burman

      Version of Record online: 30 SEP 2012 | DOI: 10.1002/sim.5632

    3. Empirical shrinkage estimator for consistency assessment of treatment effects in multi-regional clinical trials (pages 1691–1706)

      Hui Quan, Mingyu Li, Weichung Joe Shih, Soo Peter Ouyang, Joshua Chen, Ji Zhang and Peng-Liang Zhao

      Version of Record online: 1 AUG 2012 | DOI: 10.1002/sim.5543

    4. Assessment of statistical significance and clinical relevance (pages 1707–1719)

      Meinhard Kieser, Tim Friede and Matthias Gondan

      Version of Record online: 28 SEP 2012 | DOI: 10.1002/sim.5634

    5. Multiple tests of cost-effectiveness angles (pages 1754–1762)

      G. Gutjahr and W. Brannath

      Version of Record online: 24 JUL 2012 | DOI: 10.1002/sim.5427