Statistics in Medicine

Cover image for Vol. 32 Issue 7

30 March 2013

Volume 32, Issue 7

Pages 1079–1258

  1. Featured Article

    1. Top of page
    2. Featured Article
    3. Research Articles
    1. Key multiplicity issues in clinical drug development (pages 1079–1111)

      Alex Dmitrienko, Ralph B. D'Agostino Sr. and Mohammad F. Huque

      Version of Record online: 9 OCT 2012 | DOI: 10.1002/sim.5642

  2. Research Articles

    1. Top of page
    2. Featured Article
    3. Research Articles
    1. A group sequential Holm procedure with multiple primary endpoints (pages 1112–1124)

      Yining Ye, Ai Li, Lingyun Liu and Bin Yao

      Version of Record online: 14 DEC 2012 | DOI: 10.1002/sim.5700

    2. A linear mixed model approach to compare the evolution of multiple biological rhythms (pages 1125–1135)

      Andrea Fontana, Massimiliano Copetti, Gianluigi Mazzoccoli, Theodore Kypraios and Fabio Pellegrini

      Version of Record online: 19 DEC 2012 | DOI: 10.1002/sim.5712

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    4. An improved algorithm for outbreak detection in multiple surveillance systems (pages 1206–1222)

      Angela Noufaily, Doyo G. Enki, Paddy Farrington, Paul Garthwaite, Nick Andrews and André Charlett

      Version of Record online: 2 SEP 2012 | DOI: 10.1002/sim.5595

    5. Estimation of a decreasing hazard of patients with acute coronary syndrome (pages 1223–1238)

      N. van Geloven, I. Martin, P. Damman, R.J. de Winter, J.G. Tijssen and H.P. Lopuhaä

      Version of Record online: 25 JUL 2012 | DOI: 10.1002/sim.5538

    6. Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies (pages 1246–1258)

      Roger M. Harbord, Vanessa Didelez, Tom M. Palmer, Sha Meng, Jonathan A.C. Sterne and Nuala A. Sheehan

      Version of Record online: 18 OCT 2012 | DOI: 10.1002/sim.5659