This work was financially supported by the Deutsche Forschungsgemeinschaft (SFB 625). We thank Prof. Dr. G. Bodwell for comments on the manuscript.
Fluorescent Core/Shell Nanoparticles for Specific Cell-Nucleus Staining†
Article first published online: 17 JUN 2008
Copyright © 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 4, Issue 7, pages 894–898, July 2008
How to Cite
Yin, M., Shen, J., Gropeanu, R., Pflugfelder, G. O., Weil, T. and Müllen, K. (2008), Fluorescent Core/Shell Nanoparticles for Specific Cell-Nucleus Staining. Small, 4: 894–898. doi: 10.1002/smll.200701107
- Issue published online: 11 JUL 2008
- Article first published online: 17 JUN 2008
- Manuscript Revised: 18 JAN 2008
- Manuscript Received: 12 NOV 2007
- Deutsche Forschungsgemeinschaft. Grant Number: SFB 625
- carboxylic acid;
- cell nucleus;
- core/shell nanoparticles;
Water-soluble fluorescent core/shell nanoparticles containing multiple -COOH groups are synthesized via atom-transfer radical polymerization by applying perylenediimide derivatives as the template. This novel dye combines good water-solubility and attractive optical properties. It specifically stains the cell nucleus by binding to positively charged nuclear proteins (see image).