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Preparation of Uniform Microspheres Using a Simple Fluidic Device and Their Crystallization into Close-Packed Lattices


  • This work was supported in part by an NIH Director's Pioneer Award (5DP1OD000798) and startup funds from Washington University in St. Louis. S.W.C. was also partially supported by a Korea Research Foundation Grant funded by the Korean Government (KRF-2007-357- D00080).


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Uniform microspheres using a fluidic device: A simple fluidic device is demonstrated to produce uniform microspheres with sizes ranging from 30 to 250 µm (see image). A tapping method with a concave glass is also developed to crystallize these microspheres into close-packed lattices. These techniques provide a powerful strategy for the scalable and continuous production of microspheres, as well as their crystalline lattices.