Titania thin films with hierarchical nanopore architecture are efficient hosts for Taq polymerase, which is selectively located in large-size mesopores. These biofunctional nanomaterials, highly tuned on the biomolecular length scale, are able to efficiently amplify DNA in a polymerase chain reaction. The engineered pore sizes and interconnectivity at the nanoscale are the key to bio-functionalization and enzyme performance.
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