This work was supported by the NSF (DMR-0602684) and the Harvard MRSEC (DMR-0820484). We thank Sebastian Seiffert for assistance with confocal microscopy and helpful discussions, and Kisun Yoon for assistance with SEM. This work was performed in part at the Center for Nanoscale Systems (CNS), which is supported by the NSF (ECS-0335765). JT received funding from the German Academic Exchange Service (D/08/44750) and the Fund of the Chemical Industry (Germany), which is gratefully acknowledged.
Fabrication of Polymersomes using Double-Emulsion Templates in Glass-Coated Stamped Microfluidic Devices†
Article first published online: 27 JUL 2010
Copyright © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 6, Issue 16, pages 1723–1727, August 16 2010
How to Cite
Thiele, J., Abate, A. R., Shum, H. C., Bachtler, S., Förster, S. and Weitz, D. A. (2010), Fabrication of Polymersomes using Double-Emulsion Templates in Glass-Coated Stamped Microfluidic Devices. Small, 6: 1723–1727. doi: 10.1002/smll.201000798
- Issue published online: 12 AUG 2010
- Article first published online: 27 JUL 2010
- Manuscript Received: 11 MAY 2010
- double emulsions;
- PDMS microfluidics;
The formation of polymersomes from copolymer-stabilized double emulsions in glass-coated, PDMS microfluidic devices is described. The device geometry enables separate injection of two organic solvents to form the shell phase of the double emulsion. This allows proper combination of the two solvents, which is essential for forming polymersomes.