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Keywords:

  • Ribonuclease A;
  • quantum dots;
  • nanosystem;
  • cellular imaging;
  • cytotoxicity
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CdTe quantum dot (QD) clusters are synthesized in the presence of RNase A, which acts as a biomolecular templating agent under microwave irradiation. Red shifts of photoluminescence spectra of the denatured RNase A (dRNase A)-capping QD clusters (dRQDs) are detected during a fifty-day storage period at room temperature. Native RNase-A-associated dRQDs (R-dRQDs) are functionalized with cyclic RGD peptides for synchronous targeted cancer imaging and therapy.