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Recent Progress in Nano-biotechnology: Compartmentalized Micro- and Nanoparticles via Electrohydrodynamic Co-jetting

Authors

  • Joerg Lahann

    Corresponding author
    1. Departments of Chemical Engineering, Materials Science and Engineering, Macromolecular Science and Engineering and Biomedical Engineering, University of Michigan, Ann Arbor, 48109, USA
    2. Institute of Functional Interfaces, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany
    • Departments of Chemical Engineering, Materials Science and Engineering, Macromolecular Science and Engineering and Biomedical Engineering, University of Michigan, Ann Arbor, 48109, USA.
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Abstract

Compartmentalized particles enable co-presentation of dissimilar sets of properties, thereby offering a broad design space for multifunctional particles. Electrohydrodynamic co-jetting is a simple, yet versatile fabrication technique that can be used to prepare such multicompartmental particles and fibers. Processing conditions are summarized for co-jetting of aqueous and organic polymer solutions as well as nanoparticle suspensions. Because particles can comprise distinct polymers in different compartments, selective surface modification becomes possible. The latter can result in unidirectional intera­ctions with cells or may pave new routes towards targeted drug delivery.

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