Functional Hydrogel Density Patterns Fabricated by Dip-Pen Nanolithography and Photografting

Authors

  • Tomas Rakickas,

    1. Department of Nanoengineering, Center for Physical Sciences and Technology, Savanorių 231, LT-02300 Vilnius, Lithuania
    Search for more papers by this author
  • Emma M. Ericsson,

    1. Molecular Physics, Department of Physics, Chemistry and Biology (IFM), Linköping University, SE-581 83 Linköping, Sweden
    Search for more papers by this author
  • Živilė Ruželė,

    1. Department of Nanoengineering, Center for Physical Sciences and Technology, Savanorių 231, LT-02300 Vilnius, Lithuania
    Search for more papers by this author
  • Bo Liedberg,

    Corresponding author
    1. Molecular Physics, Department of Physics, Chemistry and Biology (IFM), Linköping University, SE-581 83 Linköping, Sweden
    Current affiliation:
    1. Corresponding author for hydrogel chemistry.
    • Molecular Physics, Department of Physics, Chemistry and Biology (IFM), Linköping University, SE-581 83 Linköping, Sweden
    Search for more papers by this author
  • Ramūnas Valiokas

    Corresponding author
    1. Department of Nanoengineering, Center for Physical Sciences and Technology, Savanorių 231, LT-02300 Vilnius, Lithuania
    Current affiliation:
    1. Corresponding author for nanofabrication.
    • Department of Nanoengineering, Center for Physical Sciences and Technology, Savanorių 231, LT-02300 Vilnius, Lithuania.
    Search for more papers by this author

Abstract

original image

Fabrication of submicrometer-sized PEG hydrogel patterns by self-initiated photo­grafting and photopolymerization on molecular templates, made by dip-pen nanolithography on gold, is described. Well-defined hydrogel structures (line and dot arrays) with features protruding 10–15 nm above a homogeneous hydrogel background are obtained. They can be carboxylated and employed for obtaining reusable protein density nanoarrays.

Ancillary