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Keywords:

  • gramicidin A;
  • nanopores;
  • planar lipid bilayers (BLM);
  • ion channels;
  • sensors
Thumbnail image of graphical abstract

Light sensitive, semisynthetic ion channels allow for the modulation of multi­ple channel properties. Covalent attachment of a photoswitchable spiropyran group to the entrance of a gramicidin A ion channel enables reversible control of both conductance and channel lifetime, which show opposite trends in behavior at high and low salt concentrations.