Single-Cell-Level Microplasma Cancer Therapy

Authors

  • Jae Young Kim,

    1. Holcombe Department of Electrical and Computer Engineering, Center for Optical Materials Science and Engineering Technologies (COMSET), Clemson University, Clemson, SC 29634, USA
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  • Yanzhang Wei,

    1. Department of Biological Sciences, Clemson University Biomedical Institute, Clemson University, Greenville, SC 29605, USA
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  • Jinhua Li,

    1. Department of Biological Sciences, Clemson University Biomedical Institute, Clemson University, Greenville, SC 29605, USA
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  • Paul Foy,

    1. School of Materials Science and Engineering, Center for Optical Materials Science and Engineering Technologies (COMSET), Clemson University, Clemson, SC 29634, USA
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  • Thomas Hawkins,

    1. School of Materials Science and Engineering, Center for Optical Materials Science and Engineering Technologies (COMSET), Clemson University, Clemson, SC 29634, USA
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  • John Ballato,

    1. School of Materials Science and Engineering, Center for Optical Materials Science and Engineering Technologies (COMSET), Clemson University, Clemson, SC 29634, USA
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  • Sung-O Kim

    Corresponding author
    1. Holcombe Department of Electrical and Computer Engineering, Center for Optical Materials Science and Engineering Technologies (COMSET), Clemson University, Clemson, SC 29634, USA
    • Holcombe Department of Electrical and Computer Engineering, Center for Optical Materials Science and Engineering Technologies (COMSET), Clemson University, Clemson, SC 29634, USA.
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Abstract

original image

A flexible microplasma endoscope based on a 15 μm hollow-core glass optical fiber is fabricated, and tumor cell apoptotic analysis supports its potential use in targeted cancer therapies. The optical-fiber microplasma jet reveals antitumor activity at a certain plasma dose in animal studies.

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